Opportunity Information: Apply for RFA CA 17 036
The Human Tumor Atlas Network: Data Coordinating Center (U24) funding opportunity (RFA-CA-17-036) is a National Institutes of Health (NIH) cooperative agreement tied to the Beau Biden Cancer Moonshot Initiative, a major federal effort designed to speed up progress in cancer research. The core goal of this announcement is to support work that enables a comprehensive, high-resolution understanding of tumors as living, evolving ecosystems. Rather than treating a tumor as a single uniform mass, the program focus is on capturing the tumor microenvironment and its changing, multidimensional biology over time, including the different cell types present, their spatial organization, molecular states, and how these features shift during disease progression or treatment.
This FOA specifically aligns with a scientific priority identified by the Cancer Moonshot Blue Ribbon Panel: the Generation of Human Tumor Atlases. In practical terms, that means creating or enabling atlas-style resources that map human tumors in ways that integrate multiple layers of data (for example, genomic, transcriptomic, proteomic, imaging, spatial, and clinical annotations) to reveal how cancer develops and adapts. The emphasis on a Data Coordinating Center indicates that the funded activity is meant to serve as shared infrastructure for the broader Human Tumor Atlas Network, supporting consistent data collection, quality control, harmonization across sites, and dissemination of data and associated standards so that the resulting atlases are usable and comparable across projects.
The award mechanism is a U24 cooperative agreement, which typically indicates substantial NIH programmatic involvement compared to a standard research grant. This generally reflects the complexity of coordinating network-wide resources, aligning multiple contributing groups, and ensuring shared practices for data management and sharing. The activity category listed is Education and Health, and the opportunity is associated with multiple CFDA numbers (93.393, 93.394, 93.395, 93.396, 93.399), reflecting NIH cancer-related funding authorities that can support different components of the overall program.
Eligibility is broad across U.S.-based organizations and government entities. Eligible applicants include state, county, city or township governments, special district governments, and independent school districts, as well as public and state-controlled institutions of higher education and private institutions of higher education. The FOA also allows applications from federally recognized Native American tribal governments and other Native American tribal organizations, as well as public housing authorities/Indian housing authorities. Nonprofit organizations are eligible whether or not they have 501(c)(3) status, and for-profit organizations (other than small businesses) and small businesses may apply as well. The announcement also explicitly highlights additional eligible applicant types such as Alaska Native and Native Hawaiian Serving Institutions, Asian American Native American Pacific Islander Serving Institutions (AANAPISIs), Hispanic-serving Institutions, Historically Black Colleges and Universities (HBCUs), Tribally Controlled Colleges and Universities (TCCUs), faith-based or community-based organizations, eligible federal agencies, regional organizations, and U.S. territories or possessions.
Foreign participation is restricted in specific ways. Non-domestic (non-U.S.) entities or foreign institutions are not eligible to apply, and non-domestic components of U.S. organizations are also not eligible to apply. However, the FOA allows foreign components as defined in the NIH Grants Policy Statement, meaning a U.S. applicant can include certain foreign elements within the project when justified and compliant with NIH policy, even though a foreign organization cannot serve as the applicant institution itself.
Administratively, the opportunity was created on October 20, 2017, with an original closing date of January 18, 2018. The listing notes an award ceiling field but does not provide a numeric ceiling in the provided text, and the expected number of awards is not specified in the excerpt. Overall, the opportunity is best understood as a network-enabling grant aimed at building the data coordination backbone for a national effort to generate integrated, multidimensional human tumor atlases that can accelerate discovery, improve biological understanding of cancer ecosystems, and support the broader Cancer Moonshot mission.Apply for RFA CA 17 036
- The National Institutes of Health in the education, health sector is offering a public funding opportunity titled "Human Tumor Atlas Network: Data Coordinating Center (U24)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.393, 93.394, 93.395, 93.396, 93.399.
- This funding opportunity was created on 2017-10-20.
- Applicants must submit their applications by 2018-01-18. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Eligible applicants include: State governments, County governments, City or township governments, Special district governments, Independent school districts, Public and State controlled institutions of higher education, Native American tribal governments (Federally recognized), Public housing authorities/Indian housing authorities, Native American tribal organizations (other than Federally recognized tribal governments), Nonprofits having a 501 (c) (3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501 (c) (3) status with the IRS, other than institutions of higher education, Private institutions of higher education, For-profit organizations other than small businesses, Small businesses, Others.
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Frequently Asked Questions (FAQs)
What is this funding opportunity?
This opportunity is for "The Human Tumor Atlas Network: Data Coordinating Center (U24)" under NIH Funding Opportunity Announcement (FOA) RFA-CA-17-036. It supports a Data Coordinating Center (DCC) for the Human Tumor Atlas Network.
Which federal agency is offering this award?
The award is offered by the National Institutes of Health (NIH).
How is this opportunity connected to the Cancer Moonshot?
This FOA is tied to the Beau Biden Cancer Moonshot Initiative, a federal effort aimed at accelerating progress in cancer research. The FOA aligns with a Moonshot scientific priority focused on the Generation of Human Tumor Atlases.
What is the main scientific goal of the program?
The core goal is to enable a comprehensive, high-resolution understanding of tumors as living, evolving ecosystems. The focus goes beyond treating tumors as uniform masses and instead emphasizes understanding the tumor microenvironment and how tumor biology changes over time, including during disease progression or treatment.
What does "Human Tumor Atlas" mean in practical terms?
In practical terms, it refers to creating or enabling atlas-style resources that map human tumors by integrating multiple layers of data, such as genomic, transcriptomic, proteomic, imaging, spatial, and clinical annotations, to understand how cancer develops and adapts.
What is being funded specifically: research projects or infrastructure?
This FOA emphasizes a Data Coordinating Center, meaning the funded activity is intended to provide shared infrastructure for the broader network. The goal is to support consistent data practices and make the resulting tumor atlases usable and comparable across projects.
What are the expected responsibilities of the Data Coordinating Center?
Based on the description provided, the DCC is expected to support network-wide data functions including consistent data collection, quality control, harmonization across sites, and dissemination of data and associated standards.
What kinds of data are expected to be integrated in these tumor atlases?
The FOA describes integrating multiple data layers, including genomic, transcriptomic, proteomic, imaging, spatial, and clinical annotations.
Why is spatial and microenvironment information emphasized?
The program emphasizes capturing different cell types, their spatial organization, molecular states, and how those features shift over time. This reflects the idea that tumors behave like ecosystems with many interacting components rather than single, uniform entities.
What award mechanism is used?
The mechanism is a U24 cooperative agreement.
What does a U24 cooperative agreement imply about NIH involvement?
A U24 cooperative agreement typically indicates substantial NIH programmatic involvement compared to a standard research grant. This is generally used when coordinating complex, network-wide resources and aligning shared practices across multiple contributing groups.
What is the activity category for this opportunity?
The activity category listed is Education and Health.
Which CFDA numbers are associated with this opportunity?
The opportunity is associated with multiple CFDA numbers: 93.393, 93.394, 93.395, 93.396, and 93.399.
Who is eligible to apply?
Eligibility is broad across U.S.-based organizations and government entities. Eligible applicants include various levels of U.S. government (state, county, city or township), special district governments, independent school districts, public and state-controlled institutions of higher education, and private institutions of higher education.
Are nonprofit organizations eligible to apply?
Yes. Nonprofit organizations are eligible whether or not they have 501(c)(3) status.
Are for-profit organizations eligible to apply?
Yes. For-profit organizations (other than small businesses) may apply, and small businesses may also apply.
Are tribal governments and tribal organizations eligible?
Yes. Federally recognized Native American tribal governments and other Native American tribal organizations are included as eligible applicants.
Are U.S. territories eligible to apply?
Yes. The eligibility list explicitly includes U.S. territories or possessions.
Are specific institution types called out as eligible?
Yes. The FOA explicitly highlights additional eligible applicant types such as Alaska Native and Native Hawaiian Serving Institutions, AANAPISIs, Hispanic-serving Institutions, HBCUs, TCCUs, and faith-based or community-based organizations. It also lists eligible federal agencies and regional organizations.
Can a foreign organization apply as the main applicant?
No. Non-domestic (non-U.S.) entities or foreign institutions are not eligible to apply as the applicant institution.
Can a U.S. organization apply if part of the work will occur outside the United States?
The FOA states that non-domestic components of U.S. organizations are not eligible to apply. However, it also allows foreign components as defined in the NIH Grants Policy Statement, meaning a U.S. applicant may include certain foreign elements when justified and compliant with NIH policy.
What is the official FOA identifier?
The FOA identifier provided is RFA-CA-17-036.
When was this opportunity created?
The opportunity was created on October 20, 2017.
What was the original closing date?
The original closing date listed is January 18, 2018.
Is the award ceiling specified?
The listing notes an award ceiling field, but no numeric ceiling is provided in the information given.
Is the expected number of awards specified?
No. The expected number of awards is not specified in the provided excerpt.
What is the overarching purpose of funding a Data Coordinating Center for this network?
The purpose is to build the data coordination backbone for a national effort to generate integrated, multidimensional human tumor atlases. The DCC role is positioned as network-enabling infrastructure that supports consistent practices and broad dissemination so atlas resources are comparable and useful across projects.
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